Since the nanotechnology is rapidly growing to satisfy the human need, the legal and ethical issues come in concerned. The nanomedicine does not only face the ethical concerns about its environmental safety, consumer and the human health, but it also opposes the legal issue initially. The nanomedicine has an arduous path to proceed to be approved by the FDA in America. According to the FDA, the medical product that is approved by them will be categorized either as “drug”, “medical”, or “cosmetic” based on its functions. The approval processes for drug, medical, or cosmetic are various from one another. The drug takes more time and more complicated to be approved by the FDA because it directly affects the function or the structure of the body. The drug manufacturer needs to submit the case studies of the drug to the FDA so the agency can determine the safety and efficacy, which can take many years. Unlike the drug, the FDA requires the less complexed procedure for the “device” product when it only needs the assurance from the company. A “cosmetic” product is defined as any product that is applied to the human body with the purpose of enhancing the appearance and the attractiveness. For the present, the FDA does not have an official process to approve the cosmetic. The nanomedicine does not belong to a unique place based on the FDA category because it performs with the function of a medical device, a drug, and a cosmetic. Therefore, the nanomedicine faces a complicated path before it can be approved. The FDA will only assure the safety of the nanomedicine use but without categorizing first. Not only facing the legal issue, people express their concerns about the ethical issue. The most concern of the nanomedicine is its toxicity of nanomaterial. Many believe that it will not only hazardously affect the human body, but it also has negative impacts on the environment. There are potential risks for a patient who is treated with the nanomedicine due to the lack of knowledge about the toxicity of the nanomedicine. It also can create the contamination due to the disposal of the nanomaterial. People question their privacy and their relationship with the technology when it comes to the nanomedicine. They also fear of decreasing gap between humans and computers and soon, human will not have control or a say over their bodies. Risk will happen like particles cannot be seen or easily controlled, and it would enter the body and deliver toxic substances to unwanted locations. The use of nanomedicine as diagnosing when it enters the interior of the human body to collect the date worry human’s privacy. The development of technology already involves in the daily life of human which create anxiety of many individuals who believes that the technology will control human one day, and the nanomedicine will be the start. The nanomedicine also faces the other ethical question such as the testing of animals. The nanomedicine creation is an advanced development that will bring a lot of benefits, however, many believe that it will bring more harm due to its ethical and social implications.