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Journal Club

Journal club open for all faculty, staff, students and friends interested in current achievements in modern science.

Once per two weeks we discuss recent papers that appeared in peer-reviewed journals. Usually our journal club takes place Friday at noon, in the large conference room at Inova Fairfax Hospital, Claude Moore Building, 3rd floor.

Announcements are usually sent by e-mail the day before Journal Club.


Friday, June 14, 2010
Greg Vernon, BS Student JHU
"Chitturi and Farrell: detailed review of NASH underpinnings"

Friday, June 14, 2010
Sophia Ham, BS Student NYU
"Bariatric surgery and taste: novel mechanisms of weight loss"

Friday, June 14, 2010
Ganesh Sundar, BS Student VCU
"NAFLD serum proteomics"

Friday, April 18, 2010
Anima Sharma, ASSIP Student (BS)
“Co-occurrence NAFLD and cardiovascular disease: more than a coincidence"

Friday, June 11, 2010
Kathy Doyle, MS Student
“TLR Binding Serum DNA Sequences as Outcome Predictors"

Friday, May 14, 2010
Dr. Vladimir Kuznetsov
Bioinformatics Institute Singapore
"Biomarkers of Breast Carcinoma Survival"

Friday, April 9, 2010
Haveesh Sharma, MS Student
“Control” laboratory rodents are metabolically morbid: Why it matters."

Friday, March 26, 2010
Rohini Mehta, Ph.D. Student
“Can faulty antennae increase adiposity? The link between cilia proteins and obesity"

Friday, January 29, 2010
Amanda Zirzow, MS Student
“Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells"

Dr. Ju Young, Virginia Tech
"Influence of Soy Bean Oil on Breast Carcinoma"

Brian Lam
"Hepatocellular Carcinomas in Patients With Metabolic Syndrome Often Develop Without Significant Liver Fibrosis: A Pathological Analysis"

Juhi Moon
“Coffee Intake Is Associated with Lower Rates of Liver Disease Progression in Chronic Hepatitis C"

Shanna Bolden, MS Student
“Human gut microbiota in obesity and after gastric bypass"

Darshan Desai, BS Student
“miRNA and HCC"

Dr. Mike Estep, TRI
“PNPLA3, NAFLD, and Ethnicity"

Dr. Maria Stepanova, CLD
“Why Smoking is bad for you, but good for Society"

Wednesday, March 16, 2003
Dr. Ancha Baranova
Nat Genet 2003 Feb;33(2):203-7
Comment in: Nat Genet. 2003 Feb;33(2):114-6.
"Extensive allelic variation and ultrashort telomeres in senescent human cells".
Baird DM, Rowson J, Wynford-Thomas D, Kipling D.

  1. April 2, 2003
    Dr. Geraldine Grant
    Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D.
    "Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype."
    Hepatology. 2003 Mar;37(3):653-64.

  2. April 16, 2003
    Chris Bradburne
    "Identification of the cellular receptor for anthrax toxin".
    Nature Vol 414, Nov. 8 2001; Pg. 225-229

  3. April 30, at 10 a.m.
    Dr. Tim Born
    " Binding equilibrium isotope effects for glucose at the catalytic
    domain of human brain hexokinase " and "Glucose binding isotope effects in the ternary complex of brain hexokinase demonstrate partial relief of ground-state
    destabilization" by Lewis BE, Schramm VL. that appeared in Am Chem Soc
    2003 Apr 23;125(16):4672-3 and 4785-98

  4. Wednesday, May 14, at 10 a.m.
    Theodor V. Jordan (Theo)
    "Mastermind mediates chromatin-specific transcription and turnover of the Notch
    enhancer complex" by Fryer CJ, Lamar E, Turbachova I, Kintner C, Jones KA. that appeared in Genes and Development in 2002 Jun 1;16(11):1397-411.

  5. Wednesday, May 28, at 10 a.m.
    Mike Estep
    "Proliferative action of mast-cell tryptase is mediated by PAR2, COX2,
    prostaglandins, and PPARgamma : Possible relevance to human fibrotic
    disorders" by Frungieri MB et al.,
    Proc Natl Acad Sci U S A 2002 Nov 12;99(23):15072-7

  6. Wednesday, June 11, at 10 a.m.
    Linda M. Dickerson
    "Apoptotic conversion: evidence for exchange of genetic information between prostate cancer cells mediated by apoptosis" by de la Taille A. et al., Cancer Res 1999
    and "Horizontal transfer of oncogenes by uptake of apoptotic bodies" by Bergsmedh A et al., PNAS 2001

  7. Wednesday, June 25, at 10 a.m.
    Dion O'Mara
    "Myc activates telomerase". Genes Dev. 1998 Jun 15;12(12):1769-74. by Wang J, Xie LY, Allan S, Beach D, Hannon GJ

  8. Wednesday, July 9, at 10 a.m.
    Dr. Linda O'Reilly
    By Meyer AS, Gillespie JR, Walther D, Millet IS, Doniach S, Frydman J.
    "Closing the folding chamber of the eukaryotic chaperonin requires the transition state of ATP hydrolysis." Cell. 2003 May 2;113(3):369-81.

  9. Wednesday, July 23, at 10 a.m.
    Dr. Moniq Van Hoek
    Mohammed Zuber, Timothy A. Hoover, Mark T. Dertzbaugh, Donald L. Court
    A Francisella tularensis DNA clone complements Escherichia coli
    defective for the production of Era, an essential Ras-like
    GTP-binding protein. Gene 189 (1997) 31-34

  10. Wednesday, August 6, at 10 a.m.
    Svetlana Nazarenko
    Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol. 2003 Jun;21(6):635-7.

  11. Wednesday, August 20, at 10 a.m.
    Dr. Ancha Baranova
    Barozzi P. et al.
    Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors. Nature Medicine, May 2003
    Moore PS.
    Transplanting cancer: donor-cell transmission of Kaposi sarcoma.

  12. Wednesday, September 3, at 10 a.m.
    Won Jong Moon
    Evidence for large domains of similarly expressed genes
    in the Drosophila genome. Spellman PT, Rubin GM.
    J Biol. 2002;1(1):5. Epub 2002 Jun 18.

  13. Wednesday, October 1, at 10 a.m.
    Vatchara "Joy" Castano
    Kolettas E, Buluwela L, Bayliss MT, Muir HI.
    Expression of cartilage-specific molecules is retained on long-term culture of human
    articular chondrocytes.
    J Cell Sci. 1995 May;108 (Pt 5):1991-9.

  14. Wednesday, October 15, at 10 a.m.
    Dr. Karen Schlauch
    Importance of replication in microarray gene expression studies: Statistical methods
    and evidence from repetitive cDNA hybridizations
    Mei-Ling Ting Lee, Frank C. Kuo, G. A. Whitmorei, and Jeffrey Sklarš
    9834-9839 u PNAS u August 29, 2000 u vol. 97 u no. 18

  15. Wednesday, October 29 at 10 a.m.
    Francesco Gorreta
    "Identification of NF-kB-regulated genes induced by TNFa utilizing
    expression profiling and RNA interference"
    Anwu Zhou, Shane Scoggin, Richard B Gaynor and Noelle Sevilir Williams
    Oncogene (2003) 22, 2054-2064

  16. Wednesday, November 12 at 10 a.m.
    Dr. Barney Bishop
    "SIC, a Secreted Protein of Streptococcus pyogenes That Inactivates
    Antibacterial Peptides"
    Inga-Maria Frick, Per Akesson, Magnus Rasmussen, Artur Schmidtchen, and Lars Bjorck
    THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 278, No. 19, Issue of May 9, pp. 16561-16566, 2003

  17. Wednesday, November 26 at 10 a.m.
    Dr. Luca Del Giacco
    Thioredoxin Reductase Mediates Cell Death Effects of the
    Combination of Beta Interferon and Retinoic Acid
    MOLECULAR AND CELLULAR BIOLOGY, Nov. 1998, p. 6493-6504 Vol. 18, No. 11

  18. Wednesday, November 26 at 10 a.m.
    Amy Vam Meter
    Mengshol JA, Vincenti MP, Coon CI, Barchowsky A, Brinckerhoff CE. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum. 2000 Apr;43(4):801-11.

  19. Wednesday, November 26 at 10 a.m.
    Dagania Barzaghi
    Anderl JN, Zahller J, Roe F, Stewart PS. Role of nutrient limitation and stationary-phase existence in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob Agents Chemother. 2003 Apr;47(4):1251-6.

  20. Wednesday, January 7 at 10 a.m.
    Lesya Geraymovytch
    Linder K, Arner P, Flores-Morales A, Tollet-Egnell P, Norstedt G. Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women. J Lipid Res. 2003 Oct 16
    Boeuf S, Keijer J, Franssen-Van Hal NL, Klaus S. Individual variation of adipose gene expression and identification of covariated genes by cDNA microarrays. Physiol Genomics. 2002 Oct 2;11(1):31-6. Epub 2002 Aug 07.

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