Research Projects

TelSeq Telomere Length Nomogram Creation Utilizing TOPMed Cohorts

Development of regression-based, age-adjusted telomere length reference percentiles using whole-genome sequencing data from TOPMed cohorts and application to an interstitial lung disease cohort.

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Untangling IPF: An RNA-Seq Clustering Approach for IPF Endotyping

An exploratory transcriptomic analysis of whole blood RNA-Seq data using hierarchical clustering, gene set enrichment analysis, survival analysis, PCA, and Support Vector Machines to investigate molecular endotypes of idiopathic pulmonary fibrosis.

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Assessment of Novel Biomarkers to Predict Recurrence of Atrial Fibrillation

Prospective longitudinal investigation of novel biomarkers for predicting atrial fibrillation recurrence following catheter ablation using screening, machine learning, and cross-validated regression methods.

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Association of Androgen Deprivation Therapy Categorization and T2 Diabetes

Retrospective cohort investigation of socioeconomic factors, comorbidities, androgen deprivation therapy, and diabetes outcomes among prostate cancer patients.

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Omnibus Testing Using Summary Statistics from Biobanks

Development and validation of a computationally efficient framework for exact multimarker omnibus testing using summary statistics from large biobank datasets.

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