"Assignment 4: Medicinal Plants = SEARCH LOG" Sadaf Sherwani - Computer 25 Search for plant using scientific name: Momordica charantia Google: search term hits --------------------------------------------------------- Momordica charantia 243,000 AND hypoglycemic 23,500 AND charantin 1,680 Found useful websites such as: ~Database File: Bitter Melon, Momordica charantia, Bitter Melon ... Online Plant Database contains over 100 important rainforest medicinal plants including Bitter Melon - Momordica charantia. www.rain-tree.com/bitmelon.htm ~[FOR FREE IMAGES] Momordica charantia - Bitter melon (Cucurbitaceae) - Plants of ... This site has thumbnail images of Momordica charantia - Bitter melon (Cucurbitaceae), with links to larger images. www.hear.org/starr/hiplants/images/thumbnails/html/momordica_charantia.htm ~Bitter melon - Wikipedia, the free encyclopedia Momordica charantia is a tropical and subtropical vine of the family Cucurbitaceae, .... Wikimedia Commons has media related to:. Momordica charantia ... en.wikipedia.org/wiki/Bitter_melon ====> When scrolling down to the very bottom of the page, there are more websites about the bitter gourd that are very useful such as: -Research on Bitter Melon and other vegetables as treatment for Diabetes / Glucose level reduction, http://www.healthynerd.com/2006/08/02/bitter-melon-prickly-pear-cactus-reduce-glucose-levels-of-type-2-diabetics/ -The National Bitter Melon Council, http://www1.charanteausa.com/bittermelonstudies/ -Also gave very interesting facts about what the Bitter gourd is called around the world in different languages. ~PLANTS Profile for Momordica charantia (balsampear) | USDA PLANTS A PLANTS profile of Momordica charantia (balsampear) from the USDA PLANTS database. plants.usda.gov/java/profile?symbol=MOCH2 - ~Balsam-apple, Momordica charantia L. Momordica is a Latin word that means "to bite" and refers to the look of the uneven seeds. The species name charantia is unclear as to meaning but could be ... edis.ifas.ufl.edu/FW028 - ~Journal of Ethnopharmacology : Anti-diabetic potentials of ... Unlike Momordica charantia, the hypoglycemic effects of Andrographis paniculata have only been studied in streptozotocin-induced diabetic rats (Zhang and ... linkinghub.elsevier.com/retrieve/pii/S0378874105007129 ~Bitter melon Extract,Bitter Malon Extract.Momordica charantia ... Momordica charantia (bitter melon) is a proven hypoglycemic agent. One of the active principles responsible for this action is charantin, which is composed ... www.mdidea.com/products/herbextract/bittermelon/data.html http://linkinghub.elsevier.com/retrieve/pii/S0378874105007129 **Putting all 3 of the words together worked best to show that charantin was the insulin releasing chemical in Momordica charantia. Scirus: search term hits --------------------------------------------------------- Momordica charantia 816 journals AND hypoglycemia 20 journals The first search with Momordica charantia didn't exactly give me what I wanted, but after adding hypoglycemia to the search, I got better results. 2. Slow Acting Protein Extract from Fruit Pulp of Momordica charantia with Insulin Secretagogue and Insulinomimetic Activities. Yibchok-Anun, Sirintorn / Adisakwattana, Sirichai / Yao, Cheng Yu / Sangvanich, Polkit / Roengsumran, Sophon / Hsu, Walter Haw , Biological & pharmaceutical bulletin, 29 (6), p.1126-1131, Jun 2006 ...Thai bitter gourd (Momordica charantia) fruit pulp was extracted...antihyperglycemia/hypoglycemia was observed at 4...adipocytes revealed that M. charantia protein extract significantly...incubation. Thus, the M. charantia protein extract, a... MEDLINE/PubMed Citation on MEDLINE ScienceDirect: search term hits --------------------------------------------------------- Momordica charantia 131 articles AND charantin 15 articles AND anti-diabetic 10 articles 4. Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats Journal of Ethnopharmacology, Volume 105, Issues 1-2, 21 April 2006, Pages 196-200 B.A.S. Reyes, N.D. Bautista, N.C. Tanquilut, R.V. Anunciado, A.B. Leung, G.C. Sanchez, R.L. Magtoto, P. Castronuevo, H. Tsukamura and K.-I. Maeda [AND charantin] 7. New approach for extraction of charantin from Momordica charantia with pressurized liquid extraction Separation and Purification Technology, Volume 52, Issue 3, January 2007, Pages 416-422 Jesada Pitipanapong, Sutawadee Chitprasert, Motonobu Goto, Weena Jiratchariyakul, Mitsuru Sasaki and Artiwan Shotipruk [AND anti-diabetic] 5. Pharmacological actions and potential uses of Momordica charantia: a review Journal of Ethnopharmacology, Volume 93, Issue 1, July 2004, Pages 123-132 J. K. Grover and S. P. Yadav 7. Medicinal plants of India with anti-diabetic potential Journal of Ethnopharmacology, Volume 81, Issue 1, June 2002, Pages 81-100 J. K. Grover, S. Yadav and V. Vats ----click on 2.28. Momordica charantia: Karela (Hindi) and Bitter Gourd (English) ACS: search term hits --------------------------------------------------------- Momordica charantia (sorted by relevance) 44 documents search within "diabetes" 12 documents ~Cucurbitane-Type Triterpenoids from Momordica charantia Chang, C.-I; Chen, C.-R.; Liao, Y.-W.; Cheng, H.-L.; Chen, Y.-C.; Chou, C.-H. J. Nat. Prod.; (Article); 2006; 69(8); 1168-1171. DOI: 10.1021/np068008v Abstract Full: HTML / PDF (48k) http://pubs.acs.org/cgi-bin/article.cgi/jnprdf/2006/69/i08/html/np068008v.html PDF= showed that many cucurbitane-type triterpenoids have been isolated from stems of M.charantia stems from Taiwan and shows pictures of the chemical structure of these 6 types OTHER SEARCHES ~ChemFinder.com --- search "charantin" --- no results ~SDBS Spectral Database --- search "charantin" --- no results ~Chem Information SIS --- search "charantin" -- no results ~NLM NIH --- search "charantin" -- changed to "charantia" -- found Momordica charantia -- no help at all. Only told that "A plant species of the family CUCURBITACEAE. It is a source of ribosome-inactivating proteins and triterpene glycosides." ~NIST ---- search "charantin" OR "charantia" OR "momordica"-- no results ~ChemInfo -- search "momordica charantia" OR "charantin" -- no results ~GMU Online Catalog --- search "Momordica charantia" ---- 1 encyclopedia result, Medicinal plants of the world : chemical constituents, traditional, and modern medicinal uses / by Ivan A. Ross. ~ACS Journal of Medicinal Chemistry --- search "charantia OR momordica OR charantin OR cucurbitane" --- no results ~CRC --- search "charantia OR momordica OR charantin OR cucurbitane" -- no results =============================================================================================== =============================================================================================== Search Log continued for isolation, synthesis, and structure of charantin INFOMINE database Search Hits ================================================== Momordica charantia 1 Found The Cucurbit Network http://www.cucurbit.org/ no help. only images of bitter melons. SCIENCE DIRECT database Search Hits ================================================== Momordica charantia 132 AND isolation 51 AND charantin 15 (both 'AND' together) 7 ~~The effect of Momordica charantia capsule preparation on glycemic control in Type 2 Diabetes Mellitus needs further studies Journal of Clinical Epidemiology, Volume 60, Issue 6, June 2007, Pages 554-559 Antonio Miguel Limcaco Dans, Maria Vanessa C. Villarruz, Cecilia A. Jimeno, Mark Anthony U. Javelosa, Joel Chua, Rhida Bautista and Gwyneth Giselle B. Velez SummaryPlus | Full Text + Links | PDF (97 K) You are entitled to access the full text of this document [SAVED PDF FROM HERE IN FLASH DRIVE as Mcharantia article.pdf] Within References of this Journal [2] Torres, W. Momordica Charantia Linn (Family Cucurbitae–Chemistry and Pharmacology. Available at: http://www.charanteausa.com/ampalaya_archive/studies/1.doc. [SAVED DOCUMENT TO FLASH DRIVE as pharmocology.docx] ~~Pharmacological actions and potential uses of Momordica charantia: a review Journal of Ethnopharmacology, Volume 93, Issue 1, July 2004, Pages 123-132 J. K. Grover and S. P. Yadav SummaryPlus | Full Text + Links | PDF (145 K) Within References of this Journal: Parkash, A., Ng, T.B. and Tso, W.W., 2002. Purification and characterization of previous termcharantin,next term a napin-like ribosome-inactivating peptide from bitter gourd (Momordica charantia) seeds. Journal of Peptide Research 59, pp. 197–202. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (11) [SAVED PDF TO FLASH DRIVE as Purification of.pdf] ~~New approach for extraction of charantin from Momordica charantia with pressurized liquid extraction Separation and Purification Technology, Volume 52, Issue 3, January 2007, Pages 416-422 Jesada Pitipanapong, Sutawadee Chitprasert, Motonobu Goto, Weena Jiratchariyakul, Mitsuru Sasaki and Artiwan Shotipruk SummaryPlus | Full Text + Links | PDF (516 K) [SAVED PDF TO FLASH DRIVE as extraction of.pdf] ISI WEB OF KNOWLEDGE database Search Hits ================================================== Momordica charantia 204 AND charantin* 3 nothing useful Organic Syntheses Database Search Hits ================================================== Momordica charantia 0 AND charantin 0 ACS Search Hits ================================================== Momordica charantia 9 ~~Cucurbitane-Type Triterpenoids from the Fruit of Momordica charantia Kimura, Y.; Akihisa, T.; Yuasa, N.; Ukiya, M.; Suzuki, T.; Toriyama, M.; Motohashi, S.; Tokuda, H. J. Nat. Prod.; (Note); 2005; 68(5); 807-809. DOI: 10.1021/np040218p [SAVED PDF ON FLASH DRIVE as triterpenoids frm Mcharantia.pdf] ~~ Cucurbitane-Type Triterpenoids from Momordica charantia Chang, C.-I; Chen, C.-R.; Liao, Y.-W.; Cheng, H.-L.; Chen, Y.-C.; Chou, C.-H. J. Nat. Prod.; (Article); 2006; 69(8); 1168-1171. DOI: 10.1021/np068008v Abstract Full: HTML / PDF (48k) [SAVED PDF ON FLASH DRIVE as triterpenoids frm Mcharantia 2006.pdf]