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Funding
Threat and attention in adolescent anxiety
Funding: National Institute of Mental Health
Principal Investigator: Koraly Pérez-Edgar, Ph.D.
This three-year study will examine potential differences in neural activity (particularly in the amygdala and orbitofrontal cortex) among adolescents who have either been diagnosed with an anxiety disorder or who are temperamentally at risk for anxiety disorders. In addition, the study will examine attentional biases to evocative threatening faces.
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Early behavioral and psychophysiological correlates of social processing
Funding: George Mason University Faculty Research and Development Award
Principal Investigator: Koraly Pérez-Edgar, Ph.D.
This award from George Mason University will provide funding for our new study of early behavioral and psychophysiological correlates of social processing.
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Assessing the molecular genetic links between early temperament and psychopathology in adolescence
Funding: NARSAD
Principal Investigator: Koraly Pérez-Edgar, Ph.D.
This project brings together multiple gene candidates (DRD4, 5HTT, and CRH) with a large long-term longitudinal study of children first selected in early infancy for temperamental vulnerability to behavioral inhibition, shyness, and potentially anxiety. The children, now adolescents, have been observed over time for individual differences in reactivity, behavioral inhibition, and social functioning. In this study I will examine heritable traits (such as temperament and attention) that may underlie anxiety and are potentially more amenable to genetic analysis than anxiety itself.
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The effects of early temperament on social behavior in adolescence
Funding: National Institute of Child Health and Human Development
Principal Investigator: Nathan A. Fox, Ph.D.
Co-Investigator: Koraly Pérez-Edgar, Ph.D.
This longitudinal study assesses the temperamental, cognitive, affective, and psychophysiological processes that may influence socioemotional development in adolescence in a sample of children tracked since infancy.
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Neural mechanisms of threat processing in socially inhibited and anxious children
Currently under review
Principal Investigator: Nathan A. Fox, Ph.D.
Co-Principal Investigator: Koraly Pérez-Edgar, Ph.D.
The proposed study will examine the behavioral and neural correlates of threat-related attention bias in children who are identified as displaying behavioral inhibition. Behavioral Inhibition is the best candidate for a true endophenotype for anxiety disorders. Thus, examining the mechanisms underlying one aspect of this endophenotype, namely threat related bias will be advantageous towards understanding the transition from this temperament to anxiety in children. |
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